| Identification | Back Directory | [Name]
N-ARACHIDOYL-D-ERYTHRO-SPHINGOSINE | [CAS]
7344-02-7 | [Synonyms]
CERAMIDE C20
C20 Ceramide (d18:1/20:0)
N-Arachidoyl-D-sphingosine
N-Eicosanoyl-C18-sphingosine
N-ARACHIDOYL-D-ERYTHRO-SPHINGOSINE
N-Arachidoyl-D-erythro-sphingosineCeramide C20
N-Arachidoyl-D-erythro-sphingosine, synthetical
(2S,3R,4E)-2-(Eicosanoylamino)-4-octadecene-1,3-diol
N-ARACHIDOYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL
N-(Eicosanoyl)-D-erythro-1,3-dihydroxy-2-aMino-4-trans-octadecene
N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]eicosanamide | [Molecular Formula]
C38H75NO3 | [MDL Number]
MFCD02181210 | [MOL File]
7344-02-7.mol | [Molecular Weight]
594.01 |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
89-90°C | [Boiling point ]
646.97°C (rough estimate) | [density ]
0.9431 (rough estimate) | [refractive index ]
1.5350 (estimate) | [storage temp. ]
-20°C
| [solubility ]
DMF: 0.15 mg/ml | [form ]
A crystalline solid | [pka]
13.54±0.20(Predicted) | [color ]
White to off-white | [Stability:]
Stable, but may be heat sensitive-store at-20 C. Incompatible with oxidizing agents. |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Description]
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway. Certain forms of ceramide have been shown to mediate cellular responses such as apoptosis, growth arrest, and differentiation in certain cell types. C20 Ceramide is a natural 20:0 ceramide that is abundant in the brain. It is synthesized de novo by ceramide synthases 1 and 2. | [Uses]
C20 Ceramide (cas# 7344-02-7) is a compound useful in organic synthesis. | [Definition]
ChEBI: N-icosanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as eicosanoyl. It has a role as a mouse metabolite. It is a N-acylsphingosine and a Cer(d38:1). It is functionally related to an icosanoic acid. | [IC 50]
Human Endogenous Metabolite | [References]
[1] COWART L A. Sphingolipids: players in the pathology of metabolic disease.[J]. Trends in Endocrinology and Metabolism, 2009, 20 1: 34-42. DOI: 10.1016/j.tem.2008.09.004
[2] YAEL PEWZNER-JUNG Anthony H F Shifra Ben Dor. When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis.[J]. The Journal of Biological Chemistry, 2006, 281 35: 25001-25005. DOI: 10.1074/jbc.r600010200 |
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