ChemicalBook--->CAS DataBase List--->736048-65-0

736048-65-0

Request For Quotation
736048-65-0 Structure

736048-65-0 Structure
IdentificationBack Directory
[Name]

PKC-theta inhibitor
[CAS]

736048-65-0
[Synonyms]

MDK-8650
PKC-theta inhibitor
2,4-Pyrimidinediamine, N4-[[4-(aminomethyl)cyclohexyl]methyl]-5-nitro-N2-[[2-(trifluoromethoxy)phenyl]methyl]-
[Molecular Formula]

C20H25F3N6O3
[MDL Number]

MFCD31715442
[MOL File]

736048-65-0.mol
[Molecular Weight]

454.45
Chemical PropertiesBack Directory
[Boiling point ]

597.1±60.0 °C(Predicted)
[density ]

1.356±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 62.5 mg/mL (137.53 mM)
[form ]

Solid
[pka]

10.27±0.29(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

PKC-theta inhibitor 2 is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1].
[IC 50]

PKCθ: 18 nM (IC50)
[References]

[1] Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30. DOI:10.1016/j.bmcl.2006.09.056
Spectrum DetailBack Directory
[Spectrum Detail]

PKC-theta inhibitor(736048-65-0)1HNMR
736048-65-0 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: BOC Sciences
Tel: +1-631-485-4226
Website: https://www.bocsci.com/
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: HANGZHOU LEAP CHEM CO., LTD.
Tel: +86-571-87711850
Website: www.leapchem.com
Company Name: Aladdin Scientific
Tel:
Website: www.aladdinsci.com/
Company Name: Sichuan Wei Keqi Biological Technology Co., Ltd.  
Tel: 028-81700200 18116577057
Website: https://www.weikeqi-biotech.com/
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Website: http://www.shyuanye.com
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Website: http://www.cw-bio.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 177-54423994 17754423994
Website: https://www.biochempartner.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: 021-QQ：65489617 15618227136
Website: www.atkchemical.com/
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Website: www.bio-fount.com
Company Name: Changzhou Chenhong Biotechnology Co., Ltd.  
Tel: +86-0519-85788828 +86-13775037613
Website: http://www.chemrenblock.com/
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Website: http://www.chemegen.com
Company Name: Shanghai hongqu biomedical technology co. LTD  
Tel: 88888888888
Website: www.chemicalbook.com/ShowSupplierProductsList873228/0_EN.htm
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Tags:736048-65-0 Related Product Information