| Identification | Back Directory | [Name]
Cyantraniliprole | [CAS]
736994-63-1 | [Synonyms]
DPX-HG
HGW-86
Cyazypyr
Cyantraniliprole
Cyantraniliprole 95%
Cyantraniliprole, >98%
Cyantraniliprole(HGW-86)
Cyantraniliprole Standard
cyantraniliprole Solution, 1000ppm
Cyantraniliprole Solution in Acetonitrile, 100μg/mL
(5E)-5-[(2-ACETAMIDOETHOXY)IMINO]-5-[4-(TRIFLUOROMETHYL)PHENYL]PENTANOIC ACID
3-Bromo-1-(3-chloro-2-pyridyl)-4′-cyano-2′-methyl-6′-(methylcarbamoyl)pyrazole-5-carboxanilide
-bromo-2-(3-chloropyridin-2-yl)-N-[4-cyano-2-methyl-6-(methylcarbamoyl)phenyl]pyrazole-3-carboxamide
3-bromo-1-(3-chloropyridin-2-yl)-N-(4-cyano-2-methyl-6-(methylcarbamoyl)phenyl)-1H-pyrazole-5-carboxamide
3-BroMo-1-(3-chloropyridin-2-yl)-N-[4-cyano-2-Methyl-6-[N-MethylcarbaMoyl]phenyl]-1H-pyrazole-5-carboxaMide
3-BroMo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-Methyl-6-[(MethylaMino)carbonyl]phenyl]-1H-pyrazole-5-carboxaMide
1H-Pyrazole-5-carboxamide, 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]- | [EINECS(EC#)]
680-242-7 | [Molecular Formula]
C19H14BrClN6O2 | [MDL Number]
MFCD28053506 | [MOL File]
736994-63-1.mol | [Molecular Weight]
473.71 |
| Chemical Properties | Back Directory | [Melting point ]
approximate 213℃ (dec.) | [Boiling point ]
561.3±50.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
10.03±0.70(Predicted) | [color ]
Pale Beige to Beige | [Henry's Law Constant]
5.9×1012 mol/(m3Pa) at 25℃, Maniere et al. (2011) | [Major Application]
agriculture
environmental | [InChI]
InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) | [InChIKey]
DVBUIBGJRQBEDP-UHFFFAOYSA-N | [SMILES]
N1(C2=NC=CC=C2Cl)C(C(NC2=C(C(NC)=O)C=C(C#N)C=C2C)=O)=CC(Br)=N1 | [LogP]
4.630 (est) | [EPA Substance Registry System]
1H-Pyrazole-5-carboxamide, 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]- (736994-63-1) |
| Hazard Information | Back Directory | [Description]
An insecticide for the control of chewing and sucking pests. It has a moderate aqueous solubility and is non-volatile. It is not expected to be persistent in soil or water systems. It has a low mammalian toxicity and a low potential to bioaccumulate. No significant health issues have been identified. It is highly toxic to honeybees, moderately toxic to earthworms and most aquatic species. | [Uses]
Cyantraniliprole is used as an insecticide and/or acaricide. | [Definition]
ChEBI: A carboxamide that is chlorantraniliprole in which the chlorine atom attached to the phenyl ring has been replaced by a cyano group. A ryanodine receptor agonist, it is used as insecticide for the control of whitefly, thrips, aphids, fruitflies, and fruit
orms in crops such as onions, potatoes and tomatoes. It is highly toxic to honeybees. | [Production Methods]
The commercial production of cyantraniliprole involves a multi-step synthesis starting with pyrazole and pyridine derivatives, followed by bromination, nitrile introduction, and carboxamide formation to yield the final active molecule. | [Mechanism of action]
Exhibits larvicidal activity as an orally ingested toxicant by targeting and disrupting the Ca2+ balance, Second generation ryanodine receptor, Foliar and systemic activity | [in vivo]
Cyantraniliprole (10 or 150 mg/kg, orally, for 28 consecutive days) impairs the reproductive parameters of adult female Wistar rats by inducing oxidative stress[3].
| Animal Model: | Adult female Wistar rats (67 days old)[3] | | Dosage: | 10 or 150 mg/kg | | Administration: | p.o. | | Result: | Exhibited higher level of plasma progesterone, elevated levels of lipid peroxidation in reproductive organs, increased superoxide dismutase activity in the uterus and glutathione peroxidase activity on the ovary
Exhibited an increment in estrous cycle length and diminished uterine glandular epithelium.
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| [storage]
Store at -20°C | [Pesticide Type]
Insecticide |
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