| Identification | Back Directory | [Name]
PNU-282987 (S enantiomer free base) | [CAS]
737727-12-7 | [Synonyms]
PNU-282987 (S enantiomer free base)
Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- | [Molecular Formula]
C14H17ClN2O | [MDL Number]
MFCD30536206 | [MOL File]
737727-12-7.mol | [Molecular Weight]
264.75 |
| Chemical Properties | Back Directory | [Boiling point ]
431.5±30.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
13.86±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist. | [storage]
Store at -20°C | [References]
[1] Bodnar AL, et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48(4):905-8. DOI:10.1021/jm049363q |
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