| Identification | Back Directory | [Name]
17α-Hydroxyyohimban-16α-carboxylic acid ethyl ester | [CAS]
73840-32-1 | [Synonyms]
A-38
Yohimbic acid, ethyl ester
17α-Hydroxyyohimban-16α-carboxylic acid ethyl ester | [Molecular Formula]
C22H28N2O3 | [MDL Number]
MFCD01741365 | [MOL File]
73840-32-1.mol | [Molecular Weight]
368.469 |
| Hazard Information | Back Directory | [Description]
Yohimbic acid, ethyl ester is a biochemical that has been investigated for its effects on reserpine action. Reserpine is a rarely-used antipsychotic and antihypertensive drug. | [Uses]
Yohimbic acid ethyl ester (Compound 3a) is a selective ADRA2A antagonist with an IC50 of 31 nM[1]. | [References]
[1] Chayka A, et al. Structure-Based Drug Design of ADRA2A Antagonists Derived from Yohimbine. J Med Chem. 2024 Jun 27;67(12):10135-10151. DOI:10.1021/acs.jmedchem.4c00323 |
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