| Identification | Back Directory | [Name]
Cudratricusxanthone A | [CAS]
740810-42-8 | [Synonyms]
Cudratricusxanthone A
2,3,6,8-tetrahydroxy-5-(2-methylbut-3-en-2-yl)-1-(3-methylbut-2-enyl)xanthen-9-one
2,3,6,8-Tetrahydroxy-5-(2-methyl-3-buten-2-yl)-1-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
9H-Xanthen-9-one, 5-(1,1-dimethyl-2-propen-1-yl)-2,3,6,8-tetrahydroxy-1-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C23H24O6 | [MDL Number]
MFCD17214931 | [MOL File]
740810-42-8.mol | [Molecular Weight]
396.43 |
| Chemical Properties | Back Directory | [Melting point ]
145 °C(Solv: chloroform (67-66-3)) | [Boiling point ]
626.3±55.0 °C(Predicted) | [density ]
1.315±0.06 g/cm3(Predicted) | [pka]
6.73±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Cudratricusxanthone A is isolated from Cudrania tricuspidata, and has anti-inflammatory, hepatoprotective, and anti-proliferative activities. Cudratricusxanthone A inhibits osteoclast differentiation and function in RAW 264.7 cells and mouse bone marrow monocytes[1]. | [Definition]
ChEBI: Cudratricusxanthone A is a member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 2, 3, 6 and 8, an isoprenyl group at position 1 and a 2-methylbut-3-en-2-yl group at position 5. It is isolated from the root barks of Cudrania tricuspidata and exhibits cytotoxicity towards human cancer cell lines. It has a role as a metabolite, an antineoplastic agent, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and an anti-inflammatory agent. It is a member of xanthones and a polyphenol. | [References]
[1] Choi EH, Kim EN, Jeong GS. Inhibitory effect of Cudratricusxanthone A on osteoclast differentiation and function. Phytomedicine. 2018;43:86-91. DOI:10.1016/j.phymed.2018.03.060 |
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