| Identification | Back Directory | [Name]
2-(Di-tert-butylphosphino)-1-phenylindole | [CAS]
740815-37-6 | [Synonyms]
cataCXium(R) PIntB
98% [cataCXiuM PIntB]
N-Phenyl-2-(di-tert-butylphosphino)indole
N-Phenylindol-2-yl-di-tert-butylphosphine
N-Phenyl-2-(di-t-butylphosphino)indol,98%
2-(Di-tert-butylphosphino)-1-phenylindole
ditert-butyl-(1-phenylindol-2-yl)phosphane
2-(di-tert-butylphosphino)-1-phenyl-1H-indole
2-(Di-tert-butylphosphino)-1-phenylindole 96%
N-Phenyl-2-(di-t-butylphosphino)indol, min. 98% [cataCXium(R) PIntB] | [Molecular Formula]
C22H28NP | [MDL Number]
MFCD06798302 | [MOL File]
740815-37-6.mol | [Molecular Weight]
337.438 |
| Chemical Properties | Back Directory | [Melting point ]
90-92℃ (methanol ) | [Boiling point ]
455.4±27.0 °C(Predicted) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Acetonitrile (Slightly), Benzene (Slightly), Chloroform (Slightly) | [form ]
Powder | [color ]
white to yellow | [Sensitive ]
air sensitive | [BRN ]
9924511 | [InChI]
1S/C22H28NP/c1-21(2,3)24(22(4,5)6)20-16-17-12-10-11-15-19(17)23(20)18-13-8-7-9-14-18/h7-16H,1-6H3 | [InChIKey]
HDZRDZCQFYUOHE-UHFFFAOYSA-N | [SMILES]
CC(C)(C)P(c1cc2ccccc2n1-c3ccccc3)C(C)(C)C |
| Hazard Information | Back Directory | [Chemical Properties]
White to yellow powder | [Uses]
N-Phenyl-2-(di-tert-butylphosphino)indole is a catalyst for the selective monoarylation of ammonia with different aryl bromides and chlorides. | [General Description]
sold in collaboration with Solvias AG | [reaction suitability]
reaction type: Asymmetric synthesis
reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reagent type: ligand
reaction type: Sonogashira Coupling
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling | [Synthesis]
1.6 ml (15 mmol) of TMEDA was added to 1.93 g (10 mmol) dissolved in 30 ml of hexanes within 1 . A solution of n-BuLi (6.25 ml, 10 mmol) (concentration 1.6 M in hexane) was added dropwise. after 3 hr reflux (75°C), the color deepened from yellow to orange |
| Questions And Answer | Back Directory | [Reaction]
- Useful ligand for the Pd-catalyzed amination reaction.
- Ligand used for the Pd-catalyzed arylation of phenols.
- Useful ligand for the Suzuki-Miyaura coupling.
- Ligand used for the Sonagashira reaction of aryl bromides.
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J & K SCIENTIFIC LTD.
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Energy Chemical
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www.energy-chemical.com |
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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LaaJoo
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