ChemicalBook--->CAS DataBase List--->74392-49-7

74392-49-7

74392-49-7 Structure

74392-49-7 Structure
IdentificationBack Directory
[Name]

DPHE-PHE-ARG-CHLOROMETHYLKETONE
[CAS]

74392-49-7
[Synonyms]

DPHE-PHE-ARG-CMK
H-D-PHE-PHE-ARG-CMK TFA
PPACK II, TRIFLUOROACETATE SALT
DPHE-PHE-ARG-CHLOROMETHYLKETONE
H-D-Phe-Phe-Arg-chloromethylketone
phenylalanyl-phenylalanyl-argininechloromethylketone
D-Phe-Phe-Arg Chloromethylketone Trifluoroacetate Salt
H-D-PHE-PHE-ARG-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT
D-Phe-Phe-Arg ChloroMethylketone Trifluoroacetic Acid Salt
D-Phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-L-phenylalaninamide
[Molecular Formula]

C25H33ClN6O3
[MDL Number]

MFCD00237848
[MOL File]

74392-49-7.mol
[Molecular Weight]

501.02
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[storage temp. ]

-15°C
[solubility ]

water: 100 mg/mL
[form ]

Solid
[color ]

Off-White
[Water Solubility ]

water: 100mg/mL
[Stability:]

Moisture Sensitive
[InChIKey]

UFXAQJOOAQICNE-HKBOAZHASA-N
[SMILES]

ClCC(=O)[C@@H](N[C@@H](Cc2ccccc2)C(=O)NC(=O)[C@H](N)Cc1ccccc1)CCCNC(=N)N
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

Potent and specific irreversible inhibitor of plasma and glandular kallikreins
[General Description]

Potent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme.
[Biochem/physiol Actions]

Primary TargetPlasma and glandular kallikreins
Safety DataBack Directory
[WGK Germany ]

WGK 2
[Storage Class]

11 - Combustible Solids
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