| Identification | Back Directory | [Name]
3-O-demethylfortimicin A | [CAS]
74842-47-0 | [Synonyms]
A49759
A-49759
A 49759
3-O-demethylfortimicin A | [Molecular Formula]
C16H33N5O6 | [MDL Number]
MFCD01718245 | [MOL File]
74842-47-0.mol | [Molecular Weight]
391.466 |
| Hazard Information | Back Directory | [Uses]
3-O-Demethylfortimicin A (A-49759) is an aminocyclitol antibiotic with antibacterial activity. 3-O-Demethylfortimicin A is particularly effective against Gram-negative pathogens and staphylococcus[1][2][3]. | [References]
[1] Sennello LT, et al. Single-dose pharmacokinetics of 3-O-demethylfortimicin A in humans after intravenous and intramuscular administration. Antimicrob Agents Chemother. 1986 Mar;29(3):400-4. DOI:10.1128/AAC.29.3.400
[2] Girolami RL, et al. Comparative antimicrobial activity of O-demethylfortimicin A, a derivative of fortimicin A. Antimicrob Agents Chemother. 1980 Nov;18(5):766-72. DOI:10.1128/AAC.18.5.766
[3] Yang CL, et al. Comparative vestibular toxicity study with 3-O-demethylfortimicin A disulfate and gentamicin sulfate in cats. Drug Chem Toxicol. 1987;10(3-4):237-56. DOI:10.3109/01480548709042985 |
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