| Identification | Back Directory | [Name]
H-Ala-Phe-Pro-βNA · HCl | [CAS]
749831-27-4 | [Synonyms]
H-Ala-Phe-Pro-βNA
H-ALA-PHE-PRO-ΒNA·HCL
H-Ala-Phe-Pro-βNA · HCl
L-Prolinamide, L-alanyl-L-phenylalanyl-N-2-naphthalenyl- (9CI) | [Molecular Formula]
C27H30N4O3 | [MDL Number]
MFCD00237745 | [MOL File]
749831-27-4.mol | [Molecular Weight]
458.55 |
| Hazard Information | Back Directory | [Uses]
Ala-Phe-Pro-βNA is the subsrate of prolyl tripeptidyl aminopeptidase, which is from Porphyromonas gingivalis. Ala-Phe-Pro-βNA binds to H-Ala-Ile-pyrrolidin-2-yl boronic acid for PTP39 and the E636A mutant with Ki values of 88.1 nM and 48.8 nM, respectivley[1]. | [References]
[1] Xu Y, et al. Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism. J Mol Biol. 2008 Jan 18;375(3):708-19. DOI:10.1016/j.jmb.2007.09.077 |
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