| Identification | Back Directory | [Name]
Carbamic acid, [1-(2-hydroxyethyl)cyclopropyl]-, 1,1-dimethylethyl ester (9CI) | [CAS]
753023-57-3 | [Synonyms]
2-[1-(Boc-amino)cyclopropyl]ethanol
N-Boc-1-(2-hydroxyethyl)cyclopropanamine
tert-butyl 1-(2-hydroxyethyl)cyclopropylcarbamate
tert-butyl N-[1-(2-hydroxyethyl)cyclopropyl]carbamate
1-(2-Hydroxy-ethyl)-cyclopropyl]-carbamic acid tert-butyl ester
CarbaMic acid, [1-(2-hydroxyethyl)cyclopropyl]-, 1,1-diMethylethyl ester
Carbamic acid, [1-(2-hydroxyethyl)cyclopropyl]-, 1,1-dimethylethyl ester (9CI) | [Molecular Formula]
C10H19NO3 | [MDL Number]
MFCD24444732 | [MOL File]
753023-57-3.mol | [Molecular Weight]
201.26 |
| Chemical Properties | Back Directory | [Boiling point ]
310.0±11.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
12.62±0.20(Predicted) | [Appearance]
Off-white to light yellow Solid | [InChI]
InChI=1S/C10H19NO3/c1-9(2,3)14-8(13)11-10(4-5-10)6-7-12/h12H,4-7H2,1-3H3,(H,11,13) | [InChIKey]
ZYKQKYDJZPJMEF-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(=O)NC1(CCO)CC1 |
| Hazard Information | Back Directory | [Description]
tert-Butyl (1-(2-hydroxyethyl)cyclopropyl)carbamate is a pharmaceutical intermediate compound. Its molecular structure contains a tert-butoxycarbonyl (Boc) group and a cyclopropane ring substituted with a hydroxyethyl group. The Boc group is a classic protecting group for amino groups and can be selectively deprotected in subsequent synthesis. The hydroxyl group in the hydroxyethyl moiety can be used to introduce various functional groups via reactions such as etherification, esterification and oxidation, whilst the three-membered cyclopropyl ring structure can modulate the molecular conformation and lipophilicity, enabling the construction of drug molecules containing cyclopropylamine fragments (such as antibacterial, anti-inflammatory and centrally active drugs). | [Uses]
Carbamic acid, [1-(2-hydroxyethyl)cyclopropyl]-, 1,1-dimethylethyl ester (9CI) is a hydrocarbon derivative used in organic synthesis.
| [Hazard]
Carbamic acid, [1-(2-hydroxyethyl)cyclopropyl]-, 1,1-dimethylethyl ester (9CI) causes skin irritation and serious eye irritation.It is harmful if swallowed.
| [Chemical Reactivity]
Tert-butyl N-[1-(2-hydroxyethyl)cyclopropyl]carbamate reacts with strong oxidizing agents, it's thermal decomposition can lead to release of irritating gases and vapors.
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