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7556-95-8

7556-95-8 Structure

7556-95-8 Structure
IdentificationBack Directory
[Name]

6-Nitroquinazoline
[CAS]

7556-95-8
[Synonyms]

6-Nitroquinazoline
Quinazoline, 6-nitro-
[Molecular Formula]

C8H5N3O2
[MDL Number]

MFCD18448929
[MOL File]

7556-95-8.mol
[Molecular Weight]

175.14
Chemical PropertiesBack Directory
[Melting point ]

174.5-175 °C
[Boiling point ]

346.2±15.0 °C(Predicted)
[density ]

1.437±0.06 g/cm3(Predicted)
[pka]

4.04±0.26(Predicted)
Hazard InformationBack Directory
[Uses]

6-Nitroquinazoline is an antimalarial agent. 6-Nitroquinazoline is also a substrate for human liver aldehyde oxidase[1].
[References]

[1] R C ELDERFIELD, et al. Synthesis of bz-substituted quinazolines and antimalarials from them; a contribution to the chemistry of quinazoline. J Org Chem. 1947 May;12(3):405-21. DOI:10.1016/s0968-0896(03)00438-3
[2] C Beedham, et al. Substrate specificity of human liver aldehyde oxidase toward substituted quinazolines and phthalazines: a comparison with hepatic enzyme from guinea pig, rabbit, and baboon. Arch Biochem Biophys. 1995 Jun 1;319(2):481-90. DOI:10.1006/abbi.1995.1320
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