| Identification | Back Directory | [Name]
Mc-Phe-Lys(Boc)-PAB | [CAS]
756487-18-0 | [Synonyms]
TKN87180 Mc-Phe-Lys(Boc)-PAB tert-Butyl ((S)-5-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-phenylpropanamido)-6-((4-(hydroxymethyl)phenyl)amino)-6-oxohexyl)carbamate | [Molecular Formula]
C37H49N5O8 | [MDL Number]
MFCD34186949 | [MOL File]
756487-18-0.mol | [Molecular Weight]
691.81 |
| Chemical Properties | Back Directory | [Boiling point ]
984.2±65.0 °C(Predicted) | [density ]
1.232±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.87±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
TKN87180 is a Hydrolyzable linker for making ADC conjugate. TKN87180 was first reported in Bioorganic & Medicinal Chemistry Letters (2004), 14(16), 4323-4327. This product has no formal name at the moment. | [Uses]
Mc-Phe-Lys(Boc)-PAB is an ADC linker[1]. | [References]
[1] Michael A Walker, et al. Monoclonal antibody mediated intracellular targeting of tallysomycin S(10b). Bioorg Med Chem Lett. 2004 Aug 16;14(16):4323-7. DOI:10.1016/j.bmcl.2004.05.089 |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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