ChemicalBook--->CAS DataBase List--->756487-18-0

756487-18-0

756487-18-0 Structure

756487-18-0 Structure
IdentificationBack Directory
[Name]

Mc-Phe-Lys(Boc)-PAB
[CAS]

756487-18-0
[Synonyms]

TKN87180
Mc-Phe-Lys(Boc)-PAB
tert-Butyl ((S)-5-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-phenylpropanamido)-6-((4-(hydroxymethyl)phenyl)amino)-6-oxohexyl)carbamate
[Molecular Formula]

C37H49N5O8
[MDL Number]

MFCD34186949
[MOL File]

756487-18-0.mol
[Molecular Weight]

691.81
Chemical PropertiesBack Directory
[Boiling point ]

984.2±65.0 °C(Predicted)
[density ]

1.232±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

12.87±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

TKN87180 is a Hydrolyzable linker for making ADC conjugate. TKN87180 was first reported in Bioorganic & Medicinal Chemistry Letters (2004), 14(16), 4323-4327. This product has no formal name at the moment.
[Uses]

Mc-Phe-Lys(Boc)-PAB is an ADC linker[1].
[References]

[1] Michael A Walker, et al. Monoclonal antibody mediated intracellular targeting of tallysomycin S(10b). Bioorg Med Chem Lett. 2004 Aug 16;14(16):4323-7. DOI:10.1016/j.bmcl.2004.05.089
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