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756525-96-9

756525-96-9 Structure

756525-96-9 Structure
IdentificationBack Directory
[Name]

Biotin-dPEG(R)3-benzophenone
[CAS]

756525-96-9
[Synonyms]

Biotin-dPEG(R)3-benzophenone
N1-Biotinyl-N13-(4-Benzoylbenzoyl)-4,7,10-trioxa-1,13-tridecanediamine
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[1-(4-benzoylphenyl)-1-oxo-6,9,12-trioxa-2-azapentadec-15-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-
[Molecular Formula]

C34H46N4O7S
[MDL Number]

MFCD13184950
[MOL File]

756525-96-9.mol
[Molecular Weight]

654.82
Chemical PropertiesBack Directory
[Boiling point ]

933.5±65.0 °C(Predicted)
[density ]

1.188±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

solid or viscous liquid
[pka]

13.90±0.40(Predicted)
[color ]

Off-white to light yellow
[SMILES]

O=C(NCCCOCCOCCOCCCNC(C1=CC=C(C=C1)C(C2=CC=CC=C2)=O)=O)CCCCC3C4NC(NC4CS3)=O
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

13 - Non Combustible Solids
Hazard InformationBack Directory
[Uses]

Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA [1].
[reaction suitability]

reagent type: cross-linking reagent
[References]

[1] Cuquerella MC, Lhiaubet-Vallet V, Cadet J, Miranda MA. Benzophenone photosensitized DNA damage. Acc Chem Res. 2012 Sep 18;45(9):1558-70. DOI:10.1021/ar300054e
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