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758705-70-3

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758705-70-3 Structure

758705-70-3 Structure
IdentificationBack Directory
[Name]

2-Chloro-6-Methoxypurine -9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside
[CAS]

758705-70-3
[Synonyms]

2-Chloro-6-methoxypurine-9-β-D-(2’-deoxy-2’-fluoro)arabinoriboside
2-Chloro-6-Methoxy-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine
2-Chloro-6-Methoxypurine -9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside
2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-6-methoxy-9H-purine
2-CHLORO-6-METHOXY-9-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)-9H-PURINE
[Molecular Formula]

C11H12ClFN4O4
[MDL Number]

MFCD25542515
[MOL File]

758705-70-3.mol
[Molecular Weight]

318.689
Chemical PropertiesBack Directory
[Melting point ]

197-201 °C
[Boiling point ]

504.5±60.0 °C(Predicted)
[density ]

1.89±0.1 g/cm3(Predicted)
[pka]

12.54±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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