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75921-88-9

75921-88-9 Structure

75921-88-9 Structure
IdentificationBack Directory
[Name]

Dynorphin A (swine), 2-D-alanine-6-D-arginine-14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine- (9CI)
[CAS]

75921-88-9
[Synonyms]

Dynorphin A (swine), 2-D-alanine-6-D-arginine-14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine-
Dynorphin A (swine), 2-D-alanine-6-D-arginine-14-de-L-tryptophan-15-de-L-aspartic acid-16-de-L-asparagine-17-de-L-glutamine- (9CI)
[Molecular Formula]

C76H128N24O15
[MOL File]

75921-88-9.mol
[Molecular Weight]

1617.98
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[pka]

3.31±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes[1].
[References]

[1] Wüster M, et al. Opiate activity and receptor selectivity of dynorphin1-13 and related peptides. Neurosci Lett. 1980 Oct 20;20(1):79-83. DOI:10.1016/0304-3940(80)90237-2
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