| Identification | Back Directory | [Name]
6-Methoxytricin | [CAS]
76015-42-4 | [Synonyms]
6-Methoxytricin
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-6-methoxy- | [Molecular Formula]
C18H16O8 | [MOL File]
76015-42-4.mol | [Molecular Weight]
360.31 |
| Chemical Properties | Back Directory | [Melting point ]
238-240 °C(Solv: chloroform (67-66-3); methanol (67-56-1)) | [Boiling point ]
641.7±55.0 °C(Predicted) | [density ]
1.461±0.06 g/cm3(Predicted) | [form ]
solid | [pka]
6.46±0.40(Predicted) | [InChI]
1S/C18H16O8/c1-23-13-4-8(5-14(24-2)16(13)21)11-6-9(19)15-12(26-11)7-10(20)18(25-3)17(15)22/h4-7,20-22H,1-3H3 | [InChIKey]
BVRHGBHZAQNORL-UHFFFAOYSA-N | [SMILES]
OC1=C(C(C=C(C2=CC(OC)=C(O)C(OC)=C2)O3)=O)C3=CC(O)=C1OC |
| Hazard Information | Back Directory | [Uses]
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC50 values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent[1]. | [References]
[1] Lee YK, et al. Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds. Biomed Res Int. 2017;2017:7375615. DOI:10.1155/2017/7375615 |
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