| Identification | Back Directory | [Name]
13-Deoxocarminomycin | [CAS]
76034-18-9 | [Synonyms]
R-20X
D-788-11
Antibiotic D 788-11
13-Deoxocarminomycin
13-deoxycarminomycin
13-Deoxocarminomycin I
Daunorubicin Impurity 4
(8S)-10α-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8α,11-tetrahydroxy-5,12-naphthacenedione | [Molecular Formula]
C26H29NO9 | [MDL Number]
MFCD00920083 | [MOL File]
76034-18-9.mol | [Molecular Weight]
499.513 |
| Hazard Information | Back Directory | [Uses]
13-Deoxycarminomycin is used as antitumor agents in preparation of 3''-Deamino-3''-(2"-pyrroline-1"-yl)-5-imine-13-deoxyanthracyclines. 13-Deoxycarminomycin is a doxA gene confers on the transformed host the ability to convert Daunomycin and 13-Dihydrodaunomycin to Doxorubicin. | [Definition]
ChEBI: 13-deoxycarminomycin is a cytotoxic anthracycline antibiotic that is produced by Streptomyces peucetius var. carminatus (a biochemical mutant of Streptomyces peucetius var. caesius), and is active against P-388 murine leukemia. It has a role as an antineoplastic agent and a bacterial metabolite. It is an anthracycline antibiotic, an aminoglycoside antibiotic, a member of p-quinones, a member of tetracenequinones and a tertiary alcohol. It is a conjugate base of a 13-deoxycarminomycin(1+). It derives from a hydride of a tetracene. |
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