| Identification | Back Directory | [Name]
GERANYL PYROPHOSPHATE AMMONIUM 200 | [CAS]
763-10-0 | [Synonyms]
NEROLPYROPHOSPHATE
Geranyl diphosphate
Geranyl pyrophosphate
GVVPGTZRZFNKDS-JXMROGBWSA-N
GERANYL PYROPHOSPHATE AMMONIUM 200
geranyl pyrophosphate ammonium*200 ug/vial
trans-3,7-dimethyl-2,6-octadienyl pyrophosphate
(2E)-3,7-Dimethyl-2,6-octadiene-1-ol diphosphoric acid
trans-3,7-Dimethyl-2,6-octadienyl pyrophosphate, GPP
Diphosphoric acid,P-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-
Diphosphoric acid α-[(2E)-3,7-dimethyl-2,6-octadienyl] ester
[(2E)-3,7-dimethylocta-2,6-dienyl] phosphono hydrogen phosphate | [Molecular Formula]
C10H20O7P2 | [MDL Number]
MFCD00189726 | [MOL File]
763-10-0.mol | [Molecular Weight]
365.3 |
| Chemical Properties | Back Directory | [Boiling point ]
484.2±55.0 °C(Predicted) | [density ]
1.342±0.06 g/cm3(Predicted) | [Fp ]
20 °C | [storage temp. ]
−20°C
| [form ]
liquid | [pka]
1.05±0.50(Predicted) | [CAS DataBase Reference]
763-10-0 |
| Hazard Information | Back Directory | [Uses]
Geranyl diphosphate is a key intermediate in the isoprenoid biosynthesis pathway (IBP). HY-114295 plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids[1][2]. | [Definition]
ChEBI: Geranyl diphosphate is the diphosphate of the polyprenol compound geraniol. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a geraniol. It is a conjugate acid of a geranyl diphosphate(3-). | [Biochem/physiol Actions]
Intermediate in terpene biosynthesis | [IC 50]
Human Endogenous Metabolite | [Purification Methods]
Purify the pyrophosphate by paper chromatography on Whatman No 3 MM paper in a system of isopropyl alcohol/isobutyl alcohol/ammonia/water (40:20:1:39), RF 0.77-0.82. Store it in the dark as the ammonium salt at 0o. The E-form crystallises in platelets from aqueous Me2CO, m ~120o. It dissolves in dry MeCN. Alternatively purify it through a column of Dowex AG 1x8(200-400mesh) equilibrated with 50mM NH4 formate, and elute with MeOH/H2O/NH4OH (95:5:05), then freeze-dry. [Dixit et al. J Org Chem 46 1967 1981, Beilstein 1 IV 3580.] | [References]
[1] Chhonker YS, et, al. Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS. Molecules. 2018 Dec 11;23(12):3275. DOI:10.3390/molecules23123275
[2] Chang TH, et, al. Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. Plant Cell. 2010 Feb;22(2):454-67. DOI:10.1105/tpc.109.071738 |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|