| Identification | Back Directory | [Name]
Levoprotiline | [CAS]
76496-68-9 | [Synonyms]
CGP-12103A
Levoprotiline
Levoprotilinum
R-(-)-Oxaprotiline
[R,(-)]-α-[(Methylamino)methyl]-9,10-ethanoanthracene-9(10H)-ethanol
[αR,(-)]-α-[(Methylamino)methyl]-9,10-ethanoanthracene-9(10H)-ethanol
9,10-Ethanoanthracene-9(10H)-ethanol, α-[(methylamino)methyl]-, (αR)- | [Molecular Formula]
C20H23NO | [MDL Number]
MFCD00869618 | [MOL File]
76496-68-9.mol | [Molecular Weight]
293.408 |
| Hazard Information | Back Directory | [Uses]
R-(-)-Oxaprotiline (Levoprotiline) is an antidepressant with anticholinergic and sympathostimulatory activities. R-(-)-Oxaprotiline exhibits different abilities to block norepinephrine uptake and anticholinergic activity compared to its enantiomer C 49802 B-Ba. R-(-)-Oxaprotiline in human studies shows physiological effects consistent with those in animals. Administration of R-(-)-Oxaprotiline results in a modest increase in heart rate and arterial blood pressure. Salivation is inhibited with R-(-)-Oxaprotiline, consistent with its anticholinergic properties. R-(-)-Oxaprotiline has similar effects to the established antidepressant compound Levoprotiline and has a shorter onset of action[1]. | [References]
[1] Differences of sympathomimetic and anticholinergic action of OH-maprotiline and its R (-)-enantiomer |
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