| Identification | Back Directory | [Name]
Cleomiscosin B | [CAS]
76985-93-8 | [Synonyms]
Cleomiscosin B
(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one
(2R,3R)-rel-2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-9H-pyrano[2,3-f]-1,4-benzodioxin-9-one
9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one, 2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-, (2R,3R)-rel- | [Molecular Formula]
C20H18O8 | [MDL Number]
MFCD29049461 | [MOL File]
76985-93-8.mol | [Molecular Weight]
386.35 |
| Chemical Properties | Back Directory | [Boiling point ]
632.7±55.0 °C(Predicted) | [density ]
1.403±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.65±0.35(Predicted) |
| Hazard Information | Back Directory | [Uses]
Cleomiscosin B, a coumarinolignoid, is could isloted from the seeds of Hyoscyamus niger. Cleomiscosin B has potent liver protective[1][2]. | [target]
HIV | [References]
[1] Sajeli B, et, al. Hyosgerin, a new optically active coumarinolignan, from the seeds of Hyoscyamus niger. Chem Pharm Bull (Tokyo). 2006 Apr;54(4):538-41. DOI:10.1248/cpb.54.538
[2] Kaur R, et, al. High-performance liquid chromatographic method for identification and quantification of three potent liver protective coumarinolignoids-cleomiscosin A, cleomiscosin B and cleomiscosin C-in extracts of Cleome viscosa. Biomed Chromatogr. 2010 Sep;24(9):1000-5. DOI:10.1002/bmc.1399 |
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