| Identification | Back Directory | [Name]
(H-CYS-GLY-OH)2 | [CAS]
7729-20-6 | [Synonyms]
NSC 333711
1')-disulfide
(H-CYS-GLY-OH)2
CYS[CYS-GLY]-GLY
Cys-Gly disulfide
Cys-Gly, oxidized
Cystinyl-bis-glycine
N,N'-L-Cystyldiglycine
L-CYSTINYL-BIS-GLYCINE
CYS-GLY, OXIDIZED ACETATE
Oxidized cysteinylglycine
CYS-GLY, OXIDIZED ACETATE SALT
Cys-Gly, oxidised, acetate salt
(H-Cys-Gly-OH)2 (Disulfide bond)
Glycine,L-cysteinyl-, bimol. (1®
Glycine, L-cysteinyl-, bimol. (1→1')-disulfide
2-((R)-2-Amino-3-(((R)-2-amino-3-((carboxymethyl)amino)-3-oxopropyl)disulfanyl)propanamido)acetic acid | [Molecular Formula]
C10H18N4O6S2 | [MDL Number]
MFCD00037780 | [MOL File]
7729-20-6.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Boiling point ]
788.5±60.0 °C(Predicted) | [density ]
1.535±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
PBS (pH 7.2): 1 mg/ml | [form ]
A crystalline solid | [pka]
2.72±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Cystinyl-bis-glycine is a dipeptide intermediate in the synthesis of oxidized glutathione that is composed of two cysteinylglycine peptides linked by a disulfide bond. It is formed via nonenzymatic oxidation of cysteinylglycine, a glutathione catabolite produced by γ-glutamyl transpeptidase. | [Definition]
ChEBI: An organic disulfide obtained by the oxidation of two Cys-Gly molecules which are then linked via a disulfide bond. | [References]
[1] O W GRIFFITH S S T. The apparent glutathione oxidase activity of gamma-glutamyl transpeptidase. Chemical mechanism.[J]. The Journal of Biological Chemistry, 1980, 255 11: 5011-5014.
[2] E M KOZAK S S T. Glutathione-degrading enzymes of microvillus membranes.[J]. The Journal of Biological Chemistry, 1982, 257 11: 6322-6327.
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