| Identification | Back Directory | [Name]
6-Bromo-4-methyl-2-oxo-2H-1-benzopyran-3-carboxylic acid | [CAS]
773109-55-0 | [Synonyms]
UBP714
6-Bromo-4-methyl-2-oxo-2H-chromene-3-carboxylic acid
6-Bromo-4-methyl-2-oxo-2H-1-benzopyran-3-carboxylic acid | [Molecular Formula]
C11H7BrO4 | [MDL Number]
MFCD06208402 | [MOL File]
773109-55-0.mol | [Molecular Weight]
283.07 |
| Chemical Properties | Back Directory | [Boiling point ]
436.8±45.0 °C(Predicted) | [density ]
1.752±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble15mg/mL, clear | [form ]
powder | [pka]
1.26±0.20(Predicted) | [color ]
white to beige | [Water Solubility ]
Soluble in water (50 mM) |
| Hazard Information | Back Directory | [Uses]
UBP714 exhibts agonistic activity for recombinant GluN1/GluN2 receptor by binding to the positive allosteric site (PAM) of NMDARs. UBP714 enhances NMDAR-mediated field excitatory postsynaptic potentials (f-EPSPs) in Xenopus oocytes [1]. | [storage]
+4°C | [References]
[1] Irvine MW, et al., Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochem Int. 2012 Sep;61(4):593-600. DOI:10.1016/j.neuint.2011.12.020 |
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