| Identification | Back Directory | [Name]
5 7-DIHYDROXY-4-PHENYLCOUMARIN | [CAS]
7758-73-8 | [Synonyms]
Serratin
5,7-dihydroxy-4-phenylchromen-2-one
5,7-dihydroxy-4-phenyl-2-chromenone
5,7-Dihydroxy-4-phenyl-chromen-2-one
5,7-Dihydroxy-4-phenyl-2H-chromen-2-one
5,7-dihydroxy-4-phenyl-1-benzopyran-2-one
5,7-Dihydroxy-4-phenyl-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 5,7-dihydroxy-4-phenyl- | [Molecular Formula]
C15H10O4 | [MDL Number]
MFCD01078551 | [MOL File]
7758-73-8.mol | [Molecular Weight]
254.24 |
| Chemical Properties | Back Directory | [Melting point ]
227-233 °C (lit.) | [Boiling point ]
535.5±19.0 °C(Predicted) | [density ]
1.443 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 250 mg/mL (983.32 mM) | [form ]
Solid | [pka]
7.09±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. | [storage]
Store at -20°C | [References]
[1] Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30. DOI:10.1038/s41586-019-1722-1 |
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