| Identification | Back Directory | [Name]
5-FLUORO-ALPHA-METHYLTRYPTAMINE HYDROCHLORIDE | [CAS]
776-56-7 | [Synonyms]
5-FLUORO-A-METHYLTRYPTAMINE &
5-Fluoro-α-methyltryptaminehydrochloride
5-FLUORO-ALPHA-METHYLTRYPTAMINE HYDROCHLORIDE
5-fluoro-A-methyltryptamine*hydrochloride crystal
1-(5-Fluoro-1H-indol-3-yl)propan-2-amine hydrochloride | [Molecular Formula]
C11H14ClFN2 | [MDL Number]
MFCD00035176 | [MOL File]
776-56-7.mol | [Molecular Weight]
228.69 |
| Chemical Properties | Back Directory | [Melting point ]
225-226 °C (decomp) | [storage temp. ]
−20°C | [solubility ]
DMF: 5 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml | [form ]
A crystalline solid | [CAS DataBase Reference]
776-56-7 |
| Hazard Information | Back Directory | [Uses]
5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively[1][2]. | [References]
[1] N Chairungsrilerd, et al. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998 Mar;123(5):855-62. DOI:10.1038/sj.bjp.0701695
[2] Bruce E Blough, et al. Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4754-4758. DOI:10.1016/j.bmcl.2014.07.062 |
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