| Identification | Back Directory | [Name]
N-Me-L-Ala-maytansinol | [CAS]
77668-69-0 | [Synonyms]
AP3 Intermidate
AP3 Intermidate 1
N-Me-L-Ala-maytansinol
Maytansine, N2'-deacetyl-
maytansinol 3-(S)-α-N-methylaminopropionate | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C32H44ClN3O9 | [MDL Number]
MFCD32263382 | [MOL File]
77668-69-0.mol | [Molecular Weight]
650.16 |
| Chemical Properties | Back Directory | [Boiling point ]
849.5±65.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.82±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Maytansinoid-Ala is a potent microtubule-targeted compound that inhibits proliferation of cells at mitosis. Maytansinoid-Ala can be used for synthesis of ADCs. The microtubule-targeting maytansinoids accumulate in cells and induce mitotic arrest at 250- to 1000-fold lower concentrations than those required for their association with tubulin or microtubules. |
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