| Identification | Back Directory | [Name]
Rigin | [CAS]
77727-17-4 | [Synonyms]
RIGIN
DermaPep A410
Tetrapeptide-7
Rigin H-Gly-Gln-Pro-Arg-OH
Glycyl-L-glutaminyl-L-prolyl-L-arginine
L-Arginine,glycyl-L-glutaminyl-L-prolyl-
Palmitoyl Tetrapeptide-3, Palmitoyl Tetrapeptide-7
Palmitoyl Tetrapeptide-7, DermaPep A410, Regestril
(2S)-2-[[(2S)-1-[(2S)-2-[(2-aminoacetyl)amino]-4-carbamoyl-butanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[(2-aminoacetyl)amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid | [EINECS(EC#)]
232-660-2 | [Molecular Formula]
C18H32N8O6 | [MDL Number]
MFCD00076880 | [MOL File]
77727-17-4.mol | [Molecular Weight]
456.5 |
| Questions And Answer | Back Directory | [Skin Benifits]
Palmitoyl tetrapeptide-7 is derived from dehydroepiandosterone, a steroid normally synthesized and
released from the adrenal gland. DHEA has been shown to reduce inflammation, support wound healing,
and slow down the skin aging process. The ability of palmitoyl tetrapeptide-7 downregulates IL-6 and other proinflammatory cytokines has been shown to be comparable to anti-inflammatory properties of
DHEA in vitro in both resting cells and cells stressed with inflammation. Rigin, a cream containing
Palmitoyl tetrapeptide-7, has been shown to improve skin elasticity and texture. |
| Chemical Properties | Back Directory | [density ]
1.57±0.1 g/cm3(Predicted) | [pka]
3.60±0.21(Predicted) | [Sequence]
Gly-Gln-Pro-Arg | [InChIKey]
UEJYSALTSUZXFV-SRVKXCTJSA-N | [SMILES]
C(O)(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)CN |
| Hazard Information | Back Directory | [Description]
Rigin is a tuftsin-like tetrapeptide with the sequence G-Q-P-R that is derived from IgG. Rigin exhibits immunomodulatory activity, stimulating phagocytosis, activating polymorphonuclear lymphocytes and macrophages, and protecting against stress-induced damage. | [Uses]
Rigin is a synthetic peptide that is a fragment of immunoglobulin G. It binds to palmitic acid, making it more lipophilic and thus enhancing its affinity for human skin. Rigin is the active ingredient in the drug MELAO MATRIXYL 3000 SERUM, which promotes the production of facial collagen. It is also used as a pharmaceutical intermediate for the preparation of biologically active drugs. | [Definition]
ChEBI: Rigin is an oligopeptide. |
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| Company Name: |
Henan Alfachem Co.,Ltd.
|
| Telephone: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
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