| Identification | Back Directory | [Name]
2-phenylpyrazolo(4,3-c)quinolin-3(5H)-one | [CAS]
77779-60-3 | [Synonyms]
CGS-8216
2-phenylpyrazolo(4,3-c)quinolin-3(5H)-one
2,5-Dihydro-2-phenyl-3H-pyrazolo[4,3-c]quinolin-3-one | [MDL Number]
MFCD00904585 | [MOL File]
77779-60-3.mol |
| Hazard Information | Back Directory | [Uses]
CGS 8216, a benzodiazepine receptor antagonist, inhibits 3H-flunitrazepam (3H-FLU) binding to rat synaptosomal membranes in vitro at subnanomolar concentrations[1][2]. | [References]
[1] A J Czernik, et al. CGS 8216: receptor binding characteristics of a potent benzodiazepine antagonist. Life Sci. 1982 Jan 25;30(4):363-72. DOI:10.1016/0024-3205(82)90573-2
[2] M Jedrychowski, et al. Metabolic fate of CGS 8216, a benzodiazepine receptor antagonist, in rat and in man. Psychopharmacology (Berl). 1986;88(4):529-30. DOI:10.1007/BF00178521 |
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