ChemicalBook--->CAS DataBase List--->78-28-4

78-28-4

78-28-4 Structure

78-28-4 Structure
IdentificationBack Directory
[Name]

emylcamate
[CAS]

78-28-4
[Synonyms]

JD 91
MK-250
Statran
Nuncital
KABI-925
Striatran
emylcamate
3-methylpentan-3-yl carbamate
3-Pentanol, 3-Methyl-, 3-carbaMate
carbamic acid (1-ethyl-1-methyl-propyl) ester
[EINECS(EC#)]

201-101-4
[Molecular Formula]

C7H15NO2
[MDL Number]

MFCD00868182
[MOL File]

78-28-4.mol
[Molecular Weight]

145.2
Chemical PropertiesBack Directory
[Melting point ]

56-58.5°
[Boiling point ]

bp1.0 35°; bp0.7 24°
[density ]

0.9441 (estimate)
[refractive index ]

1.4206 (estimate)
[CAS DataBase Reference]

78-28-4
Hazard InformationBack Directory
[Originator]

Striatin,MSD,US,1960
[Uses]

Emylcamate is used in combination with compounds that influence brain function and or psychological state to treat herpes virus infection and outbreaks.
[Definition]

ChEBI: Emylcamate is a carbamate ester.
[Manufacturing Process]

30.5 g of 3-methyl-3-pentanol, 8.1 g of potassium cyanate and 16.3 g of trichloroacetic acid are heated while stirring at 45°C to 50°C for 24 hours, neutralized by successive addition of anhydrous sodium carbonate. The precipitate is removed from the reaction mixture. Unreacted 3-methyl-3- pentanol is distilled off and the residue is added to a small volume of distilled water. After precipitation and filtration the resulting 3-methyl-3-pentanol carbamate is dried and recrystallized from petroleum ether. MP 54°C to 55°C.
[Therapeutic Function]

Tranquilizer
[Purification Methods]

Crystallise the carbamate from 30% aqueous EtOH. [Beilstein 1 IV 1773.]
Safety DataBack Directory
[Toxicity]

LD50 oral in mouse: 760mg/kg
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