| Identification | Back Directory | [Name]
AC-MURAMYL-ALA-D-GLU(LYS(STEAROYL)-OH)-NH2 | [CAS]
78113-36-7 | [Synonyms]
nopia C13187 dj-7041 ROMURTIDE MUROCTASIN Muroetasin Muroctasine Ac-muramyl-A MDP-LYS(L 18) Romurtide USP/EP/BP )-n(sup6)-(1-oxooctadecyl)- AC-MURAMYL-ALA-D-ISOGLN-LYS(STEAROYL)-OH Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH AC-MURAMYL-ALA-D-GLU(LYS(STEAROYL)-OH)-NH2 N-acetylmuramyl-ala-D-isoglutaminyl-*N-epsilon-st N-ACETYLMURAMYL-ALA-D-ISOGLUTAMINYL-N-EP SILON-STEA n-acetylmuramyl-ala-d-isoglutaminyl-nε-stearoyl-lys N-Acetylmuramyl-alanyl-D-isoglutaminyl-N'-stearoyl-lysine N2-[(N-Acetylmuramoyl)-L-Ala-D-γGln-]-N6-stearoyl-L-Lys-OH N-ACETYLMURAMYL-ALA-D-ISO-GLUTAMINYL-N-EPSILON-STEAROYL-LYS Na-Acetylmuramyl-L-alanyl-D-isoglutaminyl-Ne-stearoyl-L-lysine n(sup2)-((n-acetylmuramoyl)-l-alanyl-d-isoglutaminyl)-n(sup6)-stearoyl-l-ly L-Lysine, N-(N-acetylmuramoyl)-L-alanyl-D-α-glutaminyl-N6-(1-oxooctadecyl)- l-lysine,n(sup2),(n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutaminyl Ac-MuraMyl-Ala-D-Isogln-Lys(stearoyl)-OH, Muroctasin, RoMurtide, MDP-Lys(L 18) L-Lysine, N-(N-acetylmuramoyl)-L-alanyl-D-a-glutaminyl-N6-(1-oxooctadecyl)- (9CI) L-Lysine, N2-[N2-[N-(N-acetylmuramoyl)-L-alanyl]-D-a-glutaminyl]-N6-(1-oxooctadecyl)- N2-[(R)-5-Amino-4-[[N-(N-acetylmuramoyl)-L-alanyl]amino]-1,5-dioxopentyl]-N6-stearoyl-L-lysine N^<2>^-[N^<2>^-[N-(N-Acetylmuramoyl)-L-alanyl]-D-α-glutaminyl]-N^<6>^-(1-oxooctadecyl)-L-lysine | [Molecular Formula]
C43H78N6O13 | [MDL Number]
MFCD00871261 | [MOL File]
78113-36-7.mol | [Molecular Weight]
887.11 |
| Chemical Properties | Back Directory | [Melting point ]
176-178° | [alpha ]
D20 +24.9° (c = 1 in methanol) | [Boiling point ]
1220.7±65.0 °C(Predicted) | [density ]
1.163±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [pka]
5.70(at 25℃) |
| Safety Data | Back Directory | [WGK Germany ]
3
| [RTECS ]
OL5545000
| [Toxicity]
LD50 in male, female mice, male, female rats, dogs (mg/kg): 436, 625, 761, 801, >200 s.c. (Ono) |
| Hazard Information | Back Directory | [Description]
Romurtide is a muramyl dipeptide which augments the production of G-CSF. The
compound is indicated as an immunomodulator for the treatment of leukopenia caused
by anticancer chemotherapy/radiotherapy and also thrombopenia. | [Chemical Properties]
White powder, odorless and tasteless. Melting point: 176-178°C. [α]D20 + 24.9° (C = 1, methanol). pKa: 5.70. Solubility at 20°C: dimethylformamide 1g/72ml; methanol 1g/190ml; ethanol 1g/330ml. Practically insoluble in acetone, acetonitrile, chloroform, or water. Acute toxicity LD50: 436, 625, 761, 801, >200 for subcutaneous injection in female mice, male and female rats, and dogs (mg/kg). | [Originator]
Daiichi (Japan) | [Definition]
ChEBI: Romurtide is an organic molecular entity. | [Brand name]
Nopia |
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| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
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