| Identification | Back Directory | [Name]
1-(4-Sulfamylphenyl)-3-trifluoromethyl-5-(7-chloroindol-3-yl)-2-pyrazoline | [CAS]
787623-48-7 | [Synonyms]
COX-2-IN-1
1-(4-Sulfamylphenyl)-3-trifluoromethyl-5-(7-chloroindol-3-yl)-2-pyrazoline
4-(5-(7-chloro-1H-indol-3-yl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide
Benzenesulfonamide, 4-[5-(7-chloro-1H-indol-3-yl)-4,5-dihydro-3-(trifluoromethyl)-1H-pyrazol-1-yl]- | [Molecular Formula]
C18H14ClF3N4O2S | [MDL Number]
MFCD31544410 | [MOL File]
787623-48-7.mol | [Molecular Weight]
442.84 |
| Hazard Information | Back Directory | [Uses]
COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM. | [IC 50]
COX-2: 3.9 μM (IC50) | [storage]
Store at -20°C | [References]
[1] Reddy MV, et al. Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors. Bioorg Med Chem. 2008 Apr 1;16(7):3907-16. DOI:10.1016/j.bmc.2008.01.047 |
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