| Identification | Back Directory | [Name]
AFP 07 (free acid) | [CAS]
788799-13-3 | [Synonyms]
AFP 07 (free acid)
PVHIRYQSPDZLLG-HBXWYSCUSA-N
AFP07 free acid,AFP 07 free acid | [Molecular Formula]
C22H30F2O5 | [MDL Number]
MFCD00951225 | [MOL File]
788799-13-3.mol | [Molecular Weight]
412.47 |
| Chemical Properties | Back Directory | [Boiling point ]
557.8±50.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml | [pka]
4.70±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
AFP-07 free acid is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM[1]. | [storage]
Store at -20°C | [References]
[1] Chang CS, et al. 7,7-Difluoroprostacyclin derivative, AFP-07, a highly selective and potent agonist for the prostacyclin receptor. Prostaglandins. 1997 Feb;53(2):83-90. DOI:10.1016/s0090-6980(97)00003-8 |
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