| Identification | Back Directory | [Name]
2-Propen-1-one, 3-(3,4-dimethoxyphenyl)-1-(2-hydroxyphenyl)-, (2E)- | [CAS]
79140-20-8 | [Synonyms]
(E)-2'-Hydroxy-3,4-dimethoxychalcone
(E)-2-(3,4-Dimethoxybenzal)-2'-hydroxyacetophenone
(E)-2-(3,4-Dimethoxybenzylidene)-2'-hydroxyacetophenone
2-Propen-1-one, 3-(3,4-dimethoxyphenyl)-1-(2-hydroxyphenyl)-, (2E)- | [Molecular Formula]
C17H16O4 | [MDL Number]
MFCD00017630 | [MOL File]
79140-20-8.mol | [Molecular Weight]
284.31 |
| Chemical Properties | Back Directory | [Melting point ]
102 °C(Solvent: Dichloromethane; Ethanol) | [Boiling point ]
466.435±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.203±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
7.768±0.30(predicted) |
| Hazard Information | Back Directory | [Uses]
(E)-2'-Hydroxy-3,4-dimethoxychalcone (compound 7) is a Chalcone derivative with orally active. (E)-2'-Hydroxy-3,4-dimethoxychalcone has anti-tumour activities[1]. | [References]
[1] Mauricio Cabrera, et al. Identification of chalcones as in vivo liver monofunctional phase II enzymes inducers. Bioorg Med Chem. 2010 Jul 15;18(14):5391-9. DOI:10.1016/j.bmc.2010.05.033 |
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