| Identification | Back Directory | [Name]
1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- | [CAS]
793729-44-9 | [Synonyms]
WAY-637471
2-(4-Fluorophenyl)-5-(((5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)thio)methyl)-1,3,4-oxadiazole
1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- | [Molecular Formula]
C15H9FN4O3S | [MOL File]
793729-44-9.mol | [Molecular Weight]
344.32 |
| Chemical Properties | Back Directory | [Boiling point ]
521.2±60.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
-5.78±0.37(Predicted) | [color ]
Yellow to brown |
| Hazard Information | Back Directory | [Uses]
Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively[1]. | [References]
[1] Early JV, et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2016 May 23;60(6):3608-16. DOI:10.1128/AAC.02896-15 |
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