| Identification | Back Directory | [Name]
PBP10 | [CAS]
794466-43-6 | [Synonyms]
PBP10
RHOB-GS160-169
RHODAMINE B-QRLFQVKGRR-OH | [Molecular Formula]
C84H127ClN24O15 | [MDL Number]
MFCD04974530 | [MOL File]
794466-43-6.mol | [Molecular Weight]
1748.51 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Solid | [color ]
White to off-white | [Water Solubility ]
Soluble to 2 mg/ml in Water | [Sequence]
RhB-Gln-Arg-Leu-Phe-Gln-Val-Lys-Gly-Arg-Arg-OH |
| Hazard Information | Back Directory | [Uses]
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1[1]. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects[2]. | [storage]
Store at -20°C | [References]
[1] C C Cunningham, et al.Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J Biol Chem DOI:10.1074/jbc.M105289200
[2] Ewelina Piktel, et al. Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin. J Nanobiotechnology. 2019 Feb 2;17(1):22. DOI:10.1186/s12951-019-0455-5 |
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| Company Name: |
BOC Sciences
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| Website: |
https://www.bocsci.com |
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