| Identification | Back Directory | [Name]
Cardol diene | [CAS]
79473-25-9 | [Synonyms]
Cardol diene
5-pentadeca-8,11-dienyl-resorcinol
5-(8,11-pentadecadienyl)-1,3-benzenediol
1,3-Benzenediol, 5-(8Z,11Z)-8,11-pentadecadien-1-yl- | [Molecular Formula]
C21H32O2 | [MOL File]
79473-25-9.mol | [Molecular Weight]
316.48 |
| Chemical Properties | Back Directory | [Boiling point ]
472.4±30.0 °C(Predicted) | [density ]
0.986±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 22 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml | [form ]
A neat oil | [pka]
9.55±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Cardol diene is a phenol found in cashew nut shell liquid. It is schistosomicidal, killing 50, 100, 100, and 100% of S. mansoni worms after 24 hours when used at concentrations of 25, 50, 100, or 200 μM, respectively. Cardol diene has an LC50 value of 32.2 μM after 24 and 48 hours against S. mansoni worms. It has been used as a starting material for the synthesis of bis-benzoxazines. | [Uses]
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability[1]. | [IC 50]
Schistosome | [References]
[1] Alvarenga TA, et al. Schistosomicidal Activity of Alkyl-phenols from the Cashew Anacardium occidentale against Schistosoma mansoni Adult Worms. J Agric Food Chem. 2016 Nov 23;64(46):8821-8827. DOI:10.1021/acs.jafc.6b04200 |
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