| Identification | Back Directory | [Name]
Pentanoic acid, 4-methyl-4-(methyldithio)- | [CAS]
796073-55-7 | [Synonyms]
Pentanoic acid, 4-methyl-4-(methyldithio)-
4-Methyl-4-(methyldisulfanyl)pentanoic acid | [Molecular Formula]
C7H14O2S2 | [MDL Number]
MFCD20639701 | [MOL File]
796073-55-7.mol | [Molecular Weight]
194.315 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C, sealed storage, away from moisture and light | [form ]
Liquid | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C7H14O2S2/c1-7(2,11-10-3)5-4-6(8)9/h4-5H2,1-3H3,(H,8,9) | [InChIKey]
GYFCEVXCVFNSCL-UHFFFAOYSA-N | [SMILES]
C(O)(=O)CCC(C)(SSC)C |
| Hazard Information | Back Directory | [Uses]
4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Disulfide Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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