| Hazard Information | Back Directory | [Description]
KBH-A42 is a histone deacetylase inhibitor. | [Uses]
KBH-A42 is a novel histone deacetylase (HDAC) inhibitor with significant anti-inflammatory properties. KBH-A42 against TNF-α and NO production with IC50 values of 1.10 and 2.71 μM, respectively, in the LPS-induced murine macrophage RAW 264.7 cells[1]. | [References]
[1] Yongseok Choi, et al. Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model. Experimental & Molecular Medicine. 2008, 40, 574-581. |
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