| Identification | Back Directory | [Name]
oMega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aMinooctadec-4-ene-1,3-diol | [CAS]
799268-47-6 | [Synonyms]
NBD Sphingosine
oMega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aMinooctadec-4-ene-1,3-diol
4-Heptadecene-1,3-diol, 2-amino-17-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-, (2S,3R,4E)-
OMEGA(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)(2S,3R,4E)-2-AMINOOCTADEC-4-ENE-1,3-DIOL;NBD SPHINGOSINE | [Molecular Formula]
C23H37N5O5 | [MDL Number]
MFCD22416765 | [MOL File]
799268-47-6.mol | [Molecular Weight]
463.57 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
powder | [InChIKey]
MNFOPKRTMFDMJV-HCEDEFRUSA-N | [SMILES]
OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21 |
| Hazard Information | Back Directory | [Uses]
NBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol may be used:
- as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine (PE)-containing liposomes
- to label sphingosine kinase 1 (SphK1) in order to determine its role in endocytic membrane trafficking
- to generate 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-ceramide C16
| [Biological Activity]
Sphingosine serves as a precursor for ceramide. It is involved in the inhibition of protein kinase C in human platelets. |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
| Company Name: |
Boao Pike
|
| Tel: |
010-57798038 15652371397 |
| Website: |
www.biopike.cn |
|