ChemicalBook--->CAS DataBase List--->79944-58-4

79944-58-4

79944-58-4 Structure

79944-58-4 Structure
IdentificationBack Directory
[Name]

Idazoxan
[CAS]

79944-58-4
[Synonyms]

Idazoxan
Idezoxane
RX-781094
dl-Idazoxan
IDAZOXAN,99%
RaceMic idazoxan
1,4-Benzodioxin, 1H-iMidazole deriv.
2-(1-Imidazoline-2-yl)-2,3-dihydro-1,4-benzodioxin
2-(2-Imidazoline-2-yl)-2,3-dihydro-1,4-benzodioxin
2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole
1H-IMidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-
[Molecular Formula]

C11H12N2O2
[MOL File]

79944-58-4.mol
[Molecular Weight]

204.23
Chemical PropertiesBack Directory
[Boiling point ]

155-165 °C(Press: 0.1 Torr)
[density ]

1.39±0.1 g/cm3(Predicted)
[pka]

9.51±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

alpha2-adrenergic blocker
[Definition]

ChEBI: A benzodioxine that is 2,3-dihydro-1,4-benzodioxine in which one of the hydrogens at position 2 has been replaced by a 4,5-dihydro-1H-imidazol-2-yl group.
[Metabolic pathway]

When rats are administered radio-labeled idazoxan orally, the biotransformation of idazoxan is by hydroxylation at the 6- and 7-positions to form phenolic metabolites, which are excreted as glucuronide and sulfate metabolites in the urine, but unconjugated in the feces. Other minor metabolic pathways are 5-hydroxylation or oxidative degradation of the imidazoline ring, but these pathways are of quantitatively minor importance in rats.
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