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799557-57-6

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799557-57-6 Structure

799557-57-6 Structure
IdentificationBack Directory
[Name]

GSK-334429
[CAS]

799557-57-6
[Synonyms]

GSK334429
GSK-334429
GSK 334429
[Molecular Formula]

C20H29F3N4O
[MOL File]

799557-57-6.mol
[Molecular Weight]

398.47
Chemical PropertiesBack Directory
[Boiling point ]

512.1±50.0 °C(Predicted)
[density ]

1.192±0.06 g/cm3(Predicted)
[pka]

8.65±0.10(Predicted)
Hazard InformationBack Directory
[Description]

GSK334429 is a histamine H3 receptor antagonist.
[Uses]

GSK334429 is a selective and orally active non-imidazole histamine H3 receptor antagonist with a pKi of 9.49 against human H3 receptor. GSK334429 can be utilized in neurological research[1].
[IC 50]

H3 Receptor: 9.49 (pKi)
[References]

[1] Medhurst AD, et al. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats. Biochem Pharmacol. 2007 Apr 15;73(8):1182-94. DOI:10.1016/j.bcp.2007.01.007
799557-57-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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