| Hazard Information | Back Directory | [Description]
GSK334429 is a histamine H3 receptor antagonist. | [Uses]
GSK334429 is a selective and orally active non-imidazole histamine H3 receptor antagonist with a pKi of 9.49 against human H3 receptor. GSK334429 can be utilized in neurological research[1]. | [IC 50]
H3 Receptor: 9.49 (pKi) | [References]
[1] Medhurst AD, et al. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats. Biochem Pharmacol. 2007 Apr 15;73(8):1182-94. DOI:10.1016/j.bcp.2007.01.007 |
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