| Identification | Back Directory | [Name]
D-erythro-sphingosine-1-phosphate (C20 base) | [CAS]
799812-75-2 | [Synonyms]
Sphingosine-1-Phosphate (d20:1)
D-erythro-sphingosine-1-phosphate (C20 base)
4-Eicosene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)-
D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE (C20 BASE);SPHINGOSINE-1-PHOSPHATE (D20:1) | [Molecular Formula]
C20H42NO5P | [MDL Number]
MFCD28143613 | [MOL File]
799812-75-2.mol | [Molecular Weight]
407.52 |
| Chemical Properties | Back Directory | [Boiling point ]
569.4±60.0 °C(Predicted) | [density ]
1.073±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
1.76±0.10(Predicted) | [InChI]
1S/C20H42NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)19(21)18-26-27(23,24)25/h16-17,19-20,22H,2-15,18,21H2,1H3,(H2,23,24,25)/b17-16+/t19-,20+/m0/s1 | [InChIKey]
YUUWWSOTAGQJFW-YIVRLKKSSA-N | [SMILES]
[H][C@](/C=C/CCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O |
| Hazard Information | Back Directory | [Uses]
D-erythro-Sphingosine-C20-1-phosphate is a growth factor-like lipid having a phosphate group. The concentration of D-erythro-Sphingosine-C20-1-phosphate in blood is a potential biomarker for early detection of cancer or vascular diseases. | [Biological Activity]
Sphingosine-1-phosphate (S1P) is an important cellular metabolite and signaling lipid in animal cells. It aids in various physiological and cellular processes such as atherosclerosisinflammationimmunitytumorigenesisand cell proliferation. S1P plays a vital role in mammalian brain and cardiac development. S1P d20:1 serves as a partial agonist at the S1P receptor 2 (S1P2). It has an ability to inhibit S1P d18:1‐mediated cyclooxygenase 2(COX2) induction. |
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Energy Chemical
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http://www.energy-chemical.com |
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Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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Creative Enzymes
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1-516-855-7709 |
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www.creative-enzymes.com |
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