| Identification | Back Directory | [Name]
N-ACETYL LEUKOTRIENE E4 | [CAS]
80115-95-3 | [Synonyms]
N-AC-LTE4
N-AcetylLTE4
N-ACETYL LEUKOTRIENE E4
leukotriene E4, N-acetyl-
5S-HYDROXY-6R-(S-(N-ACETYL)CYSTEINYL)-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID
(5S,6R,7E,9E,11Z,14Z)-5-Hydroxy-6-[[(R)-2-acetylamino-2-carboxyethyl]thio]-7,9,11,14-icosatetraenoic acid
7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-(acetylamino)-2-carboxyethyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)- | [Molecular Formula]
C25H39NO6S | [MDL Number]
MFCD00135261 | [MOL File]
80115-95-3.mol | [Molecular Weight]
481.65 |
| Hazard Information | Back Directory | [Uses]
N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine). | [storage]
Store at -20°C |
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