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802915-53-3

802915-53-3 Structure

802915-53-3 Structure
IdentificationBack Directory
[Name]

(R)-Fusarochromanone
[CAS]

802915-53-3
[Synonyms]

FC101
FC-101
FC 101
NSC 627608
NSC-627608
(R)-Fusarochromanone
4H-1-Benzopyran-4-one, 5-amino-6-[(3R)-3-amino-4-hydroxy-1-oxobutyl]-2,3-dihydro-2,2-dimethyl-
[Molecular Formula]

C15H20N2O4
[MOL File]

802915-53-3.mol
[Molecular Weight]

292.33
Chemical PropertiesBack Directory
[Boiling point ]

547.0±50.0 °C(Predicted)
[density ]

1.267±0.06 g/cm3(Predicted)
[pka]

12.45±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(R)-Fusarochromanone, is an isomer of Fusarochromanone (FC101), a small molecule fungal metabolite with a host of interesting biological functions, including very potent anti-angiogenic and direct anti-cancer activity.
[in vivo]

Fusarochromanone (8 mg/kg; IP; 5 days per week; for 3.5 weeks) Is well tolerated, non-toxic, and achieved a 30% reduction in tumor size at a dose of 8 mg/kg/day[1].

Animal Model:SCID Beige mice (CB17/Icr.Cg-PrkdcscidLystbg/Crl) injected with SRB12-p9 cells[1]
Dosage: 8 mg/kg
Administration:IP; 5 days per week; for 3.5 weeks
Result:Achieved a 30% reduction in tumor size at a dose of 8 mg/kg/day.
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