| Identification | Back Directory | [Name]
COMPLEMENT C5A, HUMAN | [CAS]
80295-54-1 | [Synonyms]
CD88
rC5a
RC5A HUMAN
complement5a
COMPLEMENT C5A
c5a anaphylatoxin
COMPLEMENT C5A, HUMAN
CD88, Complement C5a
C5A ANAPHYLATOXIN HUMAN
C5a (His-Tag) from mouse
C5a Anaphylatoxin, rC5a
COMPLEMENT C5A HUMAN, RECOMBINANT
COMPLEMENT C5A, HIS TAG(R), HUMAN
COMPLEMENT COMPONENT 5 (C5A) RECEPTOR HUMAN
COMPLEMENT C5A, HUMAN, RECOMBINANT, F. E . COLI, 100 UG
H-Thr-Leu-Gln-Lys-Lys-Ile-Glu-Glu-Ile-Ala-Ala-Lys-Tyr-Lys-His-Ser-Val-Val-Lys-Lys-Cys-Cys-Tyr-Asp-Gly-Ala-Cys-Val-Asn-Asn-Asp-Glu-Thr-Cys-Glu-Gln-Arg-Ala-Ala-Arg-Ile-Ser-Leu-Gly-Pro-Arg-Cys-Ile-Lys-Ala-Phe-Thr-Glu-Cys-Cys-Val-Val-Ala-Ser-Gln-Leu-Arg-Ala-Asn-Ile-Ser-His-Lys-Asp-Met-Gln-Leu-Gly-Arg-OH | [MDL Number]
MFCD00130842 |
| Hazard Information | Back Directory | [Uses]
Mouse complement C5a is a 77-amino acid peptide generated during complement activation from the α-chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat C5a, respectively. The 9 kDa mouse C5a protein expressed in E. coli contains a N-terminal His-Tag sequence. | [Biological Activity]
C5a binds to a signaling G-protein coupled receptor (GPCR) (C5aR/CD88)inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophilsand induces release of histamine in basophils and mast cells. |
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