| Identification | Back Directory | [Name]
ornithine-methotrexate | [CAS]
80407-73-4 | [Synonyms]
ADMPO
ornithine-methotrexate
L-Ornithine, N2-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- | [Molecular Formula]
C20H25N9O3 | [MOL File]
80407-73-4.mol | [Molecular Weight]
439.47 |
| Hazard Information | Back Directory | [Description]
Ornithine-methotrexate is a ornithine analog of methotrexate; inhibitors of dihydrofolate reductase. This decreases the tetrahydrofolate pool which then decreases synthesis of thymidyate and then inhibits DNA synthesis. | [Uses]
Ornithine-methotrexate is an active compound. | [References]
[1] Lysine and ornithine analogs of methotrexate as inhibitors of dihydrofolate reductase |
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