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80456-81-1

80456-81-1 Structure

80456-81-1 Structure
IdentificationBack Directory
[Name]

O-DESMETHYL TRAMADOL HCL
[CAS]

80456-81-1
[Synonyms]

Desmethyltramadol
O-DESMETHYL TRAMADOL HCL
O-Desmethyltramadol, O-DSMT
O-Desmethyl Tramadol DISCONTINUED. Please offer D294740
Phenol, 3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-, rel-
(+)-O-Desmethyl TramadolQ: What is (+)-O-Desmethyl Tramadol Q: What is the CAS Number of (+)-O-Desmethyl Tramadol Q: What is the storage condition of (+)-O-Desmethyl Tramadol Q: What are the applications of (+)-O-Desmethyl Tramadol
(-) O Desmethyl Tramadol D6Q: What is (-) O Desmethyl Tramadol D6 Q: What is the CAS Number of (-) O Desmethyl Tramadol D6 Q: What is the storage condition of (-) O Desmethyl Tramadol D6 Q: What are the applications of (-) O Desmethyl Tramadol D6
(+) O Desmethyl Tramadol D6Q: What is (+) O Desmethyl Tramadol D6 Q: What is the CAS Number of (+) O Desmethyl Tramadol D6 Q: What is the storage condition of (+) O Desmethyl Tramadol D6 Q: What are the applications of (+) O Desmethyl Tramadol D6
[Molecular Formula]

C15H23NO2
[MDL Number]

MFCD08063708
[MOL File]

80456-81-1.mol
[Molecular Weight]

249.35
Chemical PropertiesBack Directory
[Boiling point ]

403.3±25.0 °C(Predicted)
[density ]

1.104±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

10.00±0.10(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

O-Demethyltramadol is a primary active metabolite of Tramadol. O-Demethyltramadol is mainly responsible for its μ-opioid receptor-related analgesic effect. Tramadol is metabolized to O-Demethyltramadol mainly by the cytochrome P450 (CYP) 2D6 enzyme[1].
[Definition]

ChEBI: O-Desmethyltramadol is an alkylbenzene and a ring assembly.
[References]

[1] Lee J, et al. Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6. Drug Des Devel Ther. 2019;13:1751-1761. DOI:10.2147/DDDT.S199574
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