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80576-77-8

80576-77-8 Structure

80576-77-8 Structure
IdentificationBack Directory
[Name]

10-methyl-10-deazaaminopterin
[CAS]

80576-77-8
[Synonyms]

10-methyl-10-deazaaminopterin
10Methyl10deazaaminopterin,10 Methyl 10 deazaaminopterin
L-Glutamic acid, N-[4-[2-(2,4-diamino-6-pteridinyl)-1-methylethyl]benzoyl]-
[Molecular Formula]

C21H23N7O5
[MOL File]

80576-77-8.mol
[Molecular Weight]

453.45
Chemical PropertiesBack Directory
[density ]

1.473±0.06 g/cm3(Predicted)
[pka]

3.56±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

10-Methyl-10-deazaaminopterin is a folate analog and an antifolate. 10-Methyl-10-deazaaminopterin can be used for the research of cancer[1].
[References]

[1] Sirotnak FM, et al. New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models. Cancer Chemother Pharmacol. 1984;12(1):26-30. PMID:6690070
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