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80791-88-4

80791-88-4 Structure

80791-88-4 Structure
IdentificationBack Directory
[Name]

3'-OMe-2-NH2-A
[CAS]

80791-88-4
[Synonyms]

3'-OMe-2-NH2-A
2-Amino-3'-O-methyladenosine
3'-O-Methyl-2-AMino-adenosine
Adenosine, 2-aMino-3'-O-Methyl-
3'-O-Methyl-2,6-diaminopurine riboside
[Molecular Formula]

C11H16N6O4
[MDL Number]

MFCD15145264
[MOL File]

80791-88-4.mol
[Molecular Weight]

296.28
Hazard InformationBack Directory
[Uses]

2-Amino-3’-O-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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