| Identification | Back Directory | [Name]
AA-861 | [CAS]
80809-81-0 | [Synonyms]
AA-861
docebenone
Decebenone
AA-861
(Docebenone)
2-[12-HYDROXYDODECA-5,10-DIYNYL]-3,5,6-TRIMETHYL-P-BENZOQUINONE
2-(12-Hydroxydodecane-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone
2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione
2,5-Cyclohexadiene-1,4-dione, 2-(12-hydroxy-5,10-dodecadiyn-1-yl)-3,5,6-trimethyl- | [Molecular Formula]
C21H26O3 | [MDL Number]
MFCD00210243 | [MOL File]
80809-81-0.mol | [Molecular Weight]
326.43 |
| Hazard Information | Back Directory | [Uses]
Inhibitor (5-lipoxygenase). | [Definition]
ChEBI: A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group. | [in vivo]
Docebenone might protect experimental acute necrotizing pancreatitis in rats[3]. Docebenone suppresses the release of SRS-A by 55-97%, dose-dependently in doses of 10-8-10-5 M in monkeys. The antigen-induced SRS-A release from these fragments is dose dependently inhibited by 25-93% of Docebenone, with doses of 10-8-10-5 M[4]. | [IC 50]
5-LO |
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